Mushroom Defense Review: Powerful Health and Immune Benefits

Mushroom Defense is an organic supplement with a blend of healthy, immune-boosting mushrooms which help prevent illness and support brain health.
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What is Mushroom Defense?

Mushroom Defense formula is a nutrient and antioxidant-rich supplement containing some of the most potent ingredients nature has to offer.

The collection of fungi and mushrooms aim to strengthen the immune system, prevent bacterial and viral infections, promote energy, and reduce fatigue.

In addition, this mushroom immune defense supplement offers brain health benefits like improving memory, sharpening focus, and slowing the rate of cognitive decline.

Physicians and RDNs recommend this product highly for immune support and general health benefits. As a reviewer who has looked at a number of similar products, I have no trouble saying this is one of the best immunity defense products on the market today.

Mushroom Defense Review

Mushroom Defense Review – Image/Wellness Digest

About the Brand

The supplement manufacturer is the top health and wellness organization Leading Edge Health Ltd, which has its headquarters in Victoria, British Columbia, Canada. Founded in 1997, they are a well-regarded company which sells a number of top health supplement brands.

How We Rated

Mushroom Defense






  • The ingredients are 100% naturally sourced with no harmful additives.
  • The company is cruelty-free.
  • The manufacturing takes place in a GMP-certified facility in the USA.
  • This is a doctor and RDN-recommended supplement.

Key Ingredients

  • Agaricus Blazei
  • Shiitake
  • Lion’s Mane
  • Chaga
  • Reishi
  • Turkey Tail
  • Black Fungus
  • White Button
  • Maitake
  • Cordyceps Sinensis


  • This supplement strengthens the immune system.
  • It can enhance energy and decrease fatigue.
  • This product can improve memory and focus.
  • Mushroom Defense can prevent bacterial or viral illnesses.
  • It may slow the rate of cognitive decline.


  • Some users may be intolerant to mushrooms.
  • The results will vary for different customers.
  • There are no free samples available.
Overall Rating:4.8/ 5

Product Review – Key Facts

😊 Overall Benefits Strengthens immunity, provides energy, less chance of illness, improved memory and focus, decreases brain fog, slows cognitive decline, improves athletic performance
💊 Ingredients Turkey Tail, Lion’s Mane, Chaga, Reishi, Black Fungus, White Button, Maitake, Cordyceps Sinensis, Agaricus Blazei, Shiitake
  • 1 Month – $59.99
  • 2 Months – $109.99
  • 3 Months – $154.99
  • 6 Months – $289.99
✅ Discounts Use code SAVE15 at checkout for a 15% discount.
🏢 Company Leading Edge Health Ltd.

How Does It Work?

The formula contains a blend of fungi and mushrooms which are rich in nutrients, as well as potent antioxidants which can destroy many of the free radicals roaming your system. This lowers oxidative stress, promoting repair and healing and strengthening the immune system.

A study in Food Chemistry concluded that edible mushrooms were high in antioxidants, and this positively impacted gut health [1].

This could greatly decrease your chances of contracting viruses and bacterial infections. It has anti-inflammatory agents which lower swelling in the body and may support heart and digestive health. This product is high in fiber and also has prebiotics which feed the healthy gut bacteria.

This promotes a stronger gut microbiome, for more regular bowel movements and less issues like bloating and diarrhea. In addition, the fiber and plant protein in the formula could fill up the gut to suppress appetite.

A study in Nutrition Reviews found that dietary fiber had a positive effect on perceptions of satiety [2].

Some ingredients improve bodily circulation and enhance the transfer of oxygen to the cells, which helps boost energy and decrease fatigue. Others stimulate levels of key neurotransmitters like dopamine for brain benefits like sharper memory and focus.

What Are the Ingredients?

These are some of the primary active ingredients:


This is a mushroom full of nutrients and antioxidants, which destroy free radicals and promote improved immune functioning. It has potent anti-inflammatory agents and may decrease swelling, and there’s some evidence that it could help heal urinary tract issues [3].

It may enhance workout performance and could decrease cholesterol levels. An article in Integrative Medicine discussed the immune benefits of 5 major mushrooms, including reishi [4].


This is an edible mushroom which may balance blood sugar levels and is ideal for people who suffer from diabetes. It’s high in beta-glucan, which has a lot of fiber and can promote improved digestive health and suppress hunger.

Maitake is high in antioxidants which can heal and repair, as well as promote a strong immune system. A study in Natural Medicine Journal found that maitake had immune-system boosting benefits [5].

Lion’s Mane

This mushroom grows on the trunks of dead trees. It contains properties which help protect the nervous system and promote improved nerve cell development and function. It supports brain health and may slow the development of degenerative brain conditions.

In addition, it could enhance positive mood and decrease levels of stress and anxiety. A review published in the Journal of Agriculture and Food Chemistry discussed the health-promoting benefits of lion’s mane, as well as its chemistry and nutrition [6].

Frequently Asked Questions

Q: Who Should Take It?

A: This product is ideal for any adult who wants to improve their general health and strengthen immune functioning, as well as for those looking to decrease fatigue and enhance energy levels. It also provides benefits for those wishing to enhance cognitive functions like memory and focus.

Q: Is It Legitimate?

A: Personally I know this company very well and have taken a couple of their supplements very successfully in the past. There is no doubt they are legitimate, as they have 25 years in the industry and an excellent reputation.

There are hundreds of comments for the brand online, and many reviews for Mushroom Defense, all of which attest to the legitimacy of the brand and supplement.

Q: What is the Return Policy?

A: The manufacturer is offering a 67 day no hassle money back guarantee on their entire line. If you’re not happy with the product, get in touch with the customer service department for return instructions and then send back the bottles within 67 days of the purchase date. You should get a full refund.

Q: Where Can You Buy It?

A: This product is for sale on the official product site and on the manufacturer’s website. You can also get it from a number of other online retailers as well as offline stores.

On the official site you save money if you buy in bulk, and U.S customers who order 6 bottles or more get free shipping. At the moment you save 15% off if you use the code SAVE15 at checkout.

The prices are as follows:

  • 1 Month – $59.99
  • 2 Months – $109.99
  • 3 Months – $154.99
  • 6 Months – $289.99
Q: Is It Safe?

A: This product includes only pure, organic mushrooms and fungi, and has no chemical or artificial additives. Unless you have an intolerance to mushrooms, this is a very safe product and there should not be side effects from Mushroom Defense formula.

In addition, the company manufactures in a GMP-certified facility in the USA and does careful third-party testing.

Q: What Sets It Apart From the Competition?

A: This is a high-value product full of nutrients through a blend of enriching mushrooms and fungi. It’s a richer formula than many other products on the market, many of which focus on only one or two mushroom or fungi as ingredients. The price is very reasonable for the value.

What Do The Reviews Say?

I read through many of the Mushroom Defense reviews, and I found that most of them had very good things to say about this supplement. They mentioned that that it really helped strengthen their immune systems and prevented them from getting flus and colds.

Many noted better energy levels, as well as sharper thinking. I’ve picked out some of the best reviews to give you an idea of the general feedback:

  • Amazing Benefits
    I started taking this a few weeks ago, and I noticed the boost in energy and general well being pretty quickly. Now I wake up in the morning refreshed instead of groggy and I don’t get that midday fatigue drop. Great product; highly recommended – David
  • Haven’t Been Sick All Year

    So I’ve been taking this mushroom supplement for more than 6 months now, and I can tell you that I haven’t had one single cold or illness in all that time! In these days and times! I’ll be taking this product for a long while. Jenny R.

  • Got Rid of My Constant Fatigue

    I had this constant fatigue for years, and it was really getting in the way of my life. Since I started taking this complex, I have energy and I don’t have to lie down in the afternoon to take a nap. I really appreciate that! Clarice D.


Mushroom Defense is a natural supplement which contains a potent blend of organics that strengthen the immune system, help prevent bacterial and viral infections, provide added energy, and offer brain health benefits like improved memory and focus. It comes highly recommended by our team of physicians and RDNs.

The Mushroom Defense customer reviews had mostly very good things to say about this supplement. Many users said it cut their overall number of illnesses by quite a bit, and some mentioned not getting sick at all since they started taking it. There were no reports of discomfort or side effects.

This natural complex includes only pure organically sourced mushrooms and fungi, and it has no chemical or artificial additives or fillers. It’s a safe product which should not lead to any harmful side effects. As someone who is very familiar with the market, in my opinion this is among the very top mushroom immunity supplements available.

At Wellness Digest, our sourcing guidelines are strict and we only use primary references for our articles including peer-reviewed studies, academic research institutions, and medical associations. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  1. Edible Mushrooms Dietary Fibre And Antioxidants: Effects On Glycaemic Load Manipulation And Their Correlations Pre-And Post-Simulated In Vitro Digestion:
  2. Dietary Fiber And Satiety: The Effects Of Oats On Satiety:
  3. Randomized Clinical Trial Of An Ethanol Extract Of Ganoderma Lucidum In Men With Lower Urinary Tract Symptoms:
  4. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology:
  6. Chemistry, Nutrition, and Health-Promoting Properties of Hericium Erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds:
  7. Bioactive Ingredients and Medicinal Values of Grifola frondosa (Maitake):
  8. Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic Potential:
  9. Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials:
  10. Ganoderma Lucidum (Reishi Mushroom) For Cancer Treatment:
  11. Mushrooms and Health:
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