Perricone MD Reviews – Your Access to Ultra-Rich Beauty Solutions

Perricone MD produces a wide range of products ranging from anti-aging skincare treatments, eye treatments, Moisturizers, supplements, cleaners, toners, to masks.
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What is Perricone MD?

Perricone MD is a skincare line of products designed to help repair your damaged skin using nutrient antioxidants.

Products in this line come in three forms; clinical skincare, nutritional supplements, and an anti-inflammatory diet to make you feel and look your best every single day of your life.

Perricone MD Skincare Review

The line offers basic skincare solutions ranging from the Perricone MD No Makeup Foundation, Perricone MD No Makeup Lipstick to the Perricone Rejuvenating Moisturizer. Dermatologists highly recommend this brand, and I myself have tried several of the products and was very happy with the results they gave me.

Perricone MD Review

Perricone MD Review – Image/Wellness Digest

Overview of Perricone MD

Perricone MD


4.8/5Research Supported



Brand Highlights

  • Clinical studies and research supports the ingredients included.
  • The formulas are completely naturally-sourced.
  • They offer a free skincare consultation with a specialist.
  • They support essential workers by offering additional discounts.

Key Ingredients

  • Vitamin E
  • Ferulic Acid
  • Eggshell Membrane
  • Retinol
  • Vitamin C
  • Polyamine Growth Factor
  • Copper Tripeptide
  • Niacinamide
  • Glycerin
  • Omega 3 and 6 Fatty Acids
  • Isopropyl Palmitate


  • It can improve the firmness and elasticity of the skin.
  • Perricone MD can make the skin smooth and radiant.
  • The product can fade the signs of aging such as fine lines and wrinkles.
  • It gives your skin an even tone and texture.
  • Perricone MD can shrink enlarged pores and reduce skin redness.


  • Some people may not like the scent of certain products
  • Some products contain retinol, which may cause a slight reaction in some users.
  • Different users will experience the results differently.
Overall Rating:4.8/ 5

About the Brand: Who Owns Perricone MD?

Perricone MD a skincare company owned by Dr. Nicholas Perricone, who is an expert in healthy aging, a board-certified dermatologist, and an award-winning inventor. He has over 116 U.S and International patents for the treatment of systematic diseases and damage to the skin.

The doctor founded the company in 1997, and has since become the leading authority there on the science of fine-looking skin. He continues to make breakthroughs in the field of skincare.

Who is Dr. Perricone?

Nicholas Perricone is an American celebrity doctor. He is a board certified dermatologist, a businessman, and an author of self-help books about weight loss and maintaining the appearance of youth. He earned his medical degree from Michigan State University College of Human Medicine. (Source: Wikipedia)

Dr. Perricone’s three day and 28 day diet plans focus on eating antioxidant rich foods, high-quality proteins and vitamin supplements combined with the right topical skincare to fight the signs of aging.

Dr. Perricone no longer practices dermatology and focuses on his skincare business instead. The company was initially called NV Perricone but was rebranded to be named Perricone MD.

Perricone MD’s Philosophy and Believe

The philosophy and belief that runs Perricone MD is “We continue where nature quits.” In precise, this line comprises a three-tier wellness and skincare system that features prime products. They offer weight support solutions in form of supplements and diet ideas. The systems also consist of anti-inflammatory diets as well as offer skincare products.

Worth pointing out also is that this line tackles skin health from a holistic approach, and believes that what is seen out, comes from what is inside. In particular, the brand has a special interest in helping users control inflammation. The explanation for this is that the lack of proper nutrition is the major cause of inflammation in the body, and combined with stress and exposure to the sun, free radicals increase which consequently speeds up aging.

Perricone MD Top Products

Perricone MD sells a wide range of skincare products as well as makeup and supplements. Some of the top-selling products from this brand include:

1. Cold Plasma + Advanced Serum Concentrate Review
Cold Plasma + Advanced Serum Concentrate

The Perricone MD Cold Plasma + Advanced Serum Concentrate is a beauty product is designed to promote the 9 most noticeable symptoms of youthful-looking skin.

It works by targeting and improving skin discoloration. It also prevents enlargement of pores, skin redness, wrinkles, fine lines, and loss of skin firmness.Personally, I love this product, and I use it on a daily basis It also makes you experience a radiant and even skin texture and tone.

How to Use
Apply this serum on a cleansed skin. Gently massage it on the face and the area around the neck in an upward motion. Once it is fully absorbed into the skin, apply Perricone MD moisturizer. For better results, ensure you do this twice daily (morning and evening).

Price: $149.00

Ingredients: Vitamin C Ester, Omega 3, 6, & 9, Copper Tripeptide, Aqua, Isopropyl Palmitate, and Glycerin

See Full ReviewGet The Deal

2. Vitamin C Ester CCC + Feluric Brightening Complex 20% Review
Vitamin C Ester CCC + Feluric Brightening Complex

The Perricone MD Vitamin C Ester Brightening Serum contains powerful antioxidants and Vitamin C Ester. These components work together to brighten and smoothens your skin as well as give your skin an even tone.

How to Use
Apply it on a cleansed face and the area around the neck then massage it gently using an upward motion. Wait until it is fully absorbed then you can follow with Perricone MD Moisturizer. For best results, apply it twice in the morning and evening.

Price: $159.00

Ingredients: Vitamin C Ester, Ferulic Acid, Vitamin E, Aqua, 3-O-Ethyl Ascorbic Acid,

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3. Perricone MD High Potency Growth Factor Firming & Lifting Serum Review
Perricone MD High Potency Growth Factor Firming & Lifting Serum

It is a powerful day and night serumdesigned to give your skin a dramatic lifting effect to give it a smooth and radiant appearance. It works by supporting the skin moisture barrier and visibly improves its suppleness, cushion, bounce, strength, and resiliency.

How to Use

Apply it on a cleansed face and area around the neck. Massage it gently using an upward motion. Once it is fully absorbed, follow it with Perricone MD Moisturizer. For best results, apply it in the morning and evening.

Price: $129.00

Ingredients: Polyamine Growth Factor, Eggshell Membrane, Encapsulated Retinol, Niacinamide,

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4. Perricone MD No Makeup Foundation Review
Perricone MD No Makeup Foundation

A lightweight, balm-like primer that blurs and minimizes the look of pores, redness, wrinkles and fine lines.

How to Use

Apply evenly with fingertips or synthetic fiber brush and blend in circular motions. Reapply as necessary to build desired coverage.

Price: You can purchase it for $60

Ingredients: Cyclopentasiloxane, Dimethicone, Water, Titanium Dioxide Ci 77891)

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5. Perricone MD No Makeup Lipstick Review
Perricone MD No Makeup Lipstick

A cushiony, skincare-infused lipstick with a sheer wash of natural-looking color as it visibly improves firmness, smoothness and definition over time.

How to Use

Apply generously and evenly over the lip area. Reapply throughout the day as desired.

Price: It is available for $30 on the official website

Ingredients: Simmondsia Chinensis (Jojoba) Seed Oil, Octyldodecanol, Polyglyceryl-2 Diisostearate

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6. Perricone MD No Makeup Blush Review
Perricone MD No Makeup Blush

A lightweight, balm-like primer that blurs and minimizes the look of pores, redness, wrinkles and fine lines.

How to Use

Apply one to three dots on the apple of the cheeks and gently pat while blending in a lifting, upward motion towards the hairline.

Price: It is available for $35 on the official website

Ingredients: Titanium Dioxide (CI 77891), Iron Oxides (CI 77491, CI 77492, CI 77499), Red 7 Lake (CI 15850)

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7. Perricone MD High Potency Classics Firming Eye Lift Review
Perricone MD High Potency Classics Firming Eye Lift

This eye lift serum contains DMAE to help visibly lift sagging skin over time, while hyaluronic acid, provides essential hydration for visibly plumper skin.

How to Use

Morning and evening, gently pat onto the eye area using your ring finger. Keep out of eyes.

Price: You can buy the High Potency Classics Firming Eye Lift now for $72 on the official website

Ingredients: Water/Aqua/Eau, Isopropyl Palmitate, Cetearyl Alcohol, Taurine

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8. Perricone MD Neuropeptide Firming Moisturizer Review
Perricone MD Neuropeptide Firming Moisturizer

A luxurious, ultra-powerful formula provides essential, all-day hydration and helps dramatically and visibly firm thin and sagging skin on face.

How to Use

Massage onto a cleansed face and neck using a gentle upward motion. Use morning and evening. For best results, apply a small amount under makeup or after using Perricone MD’s Vitamin C Ester Brightening serum.

Price: It costs an eye-popping $290

Ingredients: DMAE, Water/Aqua, Tetrahexyldecyl Ascorbate, Cetearyl Alcohol, Hyaluronic Acid (HA)

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9. Perricone MD Cold Plasma Plus+ Sub-D/Neck Review
Perricone MD Cold Plasma Plus+ Sub-D/Neck

Perricone MD Cold Plasma Plus+ Sub-D/Neck promotes the most visible signs of a youthful-looking neck and a firm, sculpted jawline. In an 8-week clinical study, 85% of people had improved skin elasticity, while 76% noticed redness disappearing.

How to Use

Use morning and evening. Apply Cold Plasma Plus+ Sub-D/Neck generously to cleansed neck and jawline area.

Price: $135

Ingredients: Water, Glycolic Acid, L-Tyrosine, Dimethyl MEA (DMAE), Isopropyl Palmitate, Acetyl Carnitine Hcl, Arginine, Cetearyl Alcohol, Glyceryl Stearate

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10. Perricone MD Cold Plasma Plus Duo Review
Perricone MD Cold Plasma Plus Duo

Smooths the appearance of lines, wrinkles and uneven texture. Visibly corrects discoloration, redness and uneven skin tone.

How to Use

Apply liberally morning and evening on cleansed skin. Follow with any Perricone MD moisturizer.

Price: $199 from $259.

Ingredients: Aqua (Water), Glycerin, Tetrahexyldecyl Ascorbate, Phosphatidylcholine, Isopropyl Palmitate

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How Does Perricone MD Work?

Each product from this line is designed to benefit your skin differently. So, the product choice will depend on the kind of skin concern you have.

There are cleaners whose work is to get rid of debris that clog the pores and make your skin’s complexion dull. There are also treatments that address common skin concerns to ensure that your skin appears healthier and more attractive.

Lastly, there are hydration products that help restore the potent moisture skin barrier, leaving you feeling and looking your best.

What are the Active Ingredients in Perricone MD Products?

Vitamin C Ester

Vitamin C Ester is a potent antioxidant that supercharges the smoothing and brightening of the skin. It is the key ingredient in the Perricone MD Vitamin C Ester Brightening Serum and is specifically meant to give the skin a collagen-rich appearance, by minimizing the discoloration on your skin over time.

It does this by blocking the production of melanin on the skin, for lightening benefits. It can fade dark spots and areas of discoloration. Vitamin C Ester also hydrates the skin and eliminates dryness. It has anti-aging benefits and can help smooth wrinkles and fine lines.

Unlike other Vitamin C, this one is a fat-soluble and easy-to-absorb nutrient that maximizes antioxidant benefits. According to the Indian Dermatology Online Journal, Vitamin C contains potent antioxidant properties. It is used in dermatology treatments and prevents photoaging-related changes.

Copper Tripeptide

Copper Tripeptide is in the form of amino acid, and it works to improve the feel and look of skin’s firmness and thickness. It is one of the key ingredients in the Perricone MD Cold Plasma Plus+ Eye. The topical application of this tripeptide can improve the appearance of damaged skin, including sagging and wrinkles.

According to Current Chemical Biology, copper has been found to stimulate dermal fibroblasts proliferation as well as upregulating collagen and elastin fiber components. This helps firm the skin, improve elasticity, and smooth wrinkles and lines.

It also serves as biosynthesis, an enzyme responsible for skin pigmentation. It promotes even skin tone, eliminating age spots and acne scars. Copper tripeptides are high in anti-inflammatory agents which can reduce redness and swelling on the skin.

Encapsulated Retinol

Encapsulated Retinol is a stabilized retinol. It is used in cosmetic products to replenish the look of collagen-depleted thin skin by accelerating skin surface renewal. It is the key ingredient of the Perricone MD Firming and Lifting Serum.

This is Vitamin A, which is a powerful antioxidant which can repair skin barrier damage and protect from UV rays and pollutants. It’s also a potent exfoliant which can remove dead skin cells and dirt from the pores and help to heal acne. According to Clinical Intervention in Aging, retinoid is a potent anti-aging agent widely studied and available for the treatment of age-related symptoms.

Vitamin E

Vitamin E is a potent ingredient that provides the skin with a super nourishment effect. Its hydrating and reparative antioxidant properties aid in minimizing the appearance of discoloration on the skin, and can improve both tone and texture.

It can repair damage to the skin and protect it from UV rays. Vitamin E is also high in anti-inflammatory benefits, which can decrease redness and swelling and help to treat skin conditions.

According to the Journal of Molecular Science, Vitamin E is a naturally occurring non-enzymatic and lipid-soluble antioxidant found to protect the skin from oxidative stress adverse effects, including photoaging.

Perricone MD Discounts and Promotions

If you order any product through the subscription options helps users save some bucks. Worth noting also, that some products have higher discounts. But in general, the standard discounts under the subscription plan include;

  • 40% off for recurring orders in  the Acne category
  • 40% off for recurring orders in the dietary supplements category
  • 15% off for initial orders

The company also offers time-sensitive promotions that are activated by promo codes. This sale promotion offers a price cut of up to 50%.

Frequently Asked Questions

Q: How Clean is Perricone MD?

A: In terms of the ingredients deployed by this brand, it is safe to say Perricone MD is a clean brand. The company uses natural components that are safe for both long-term and short-term use. In addition, they cherish nature although they have some synthetic ingredients. Their focus is more on helping to restore the natural function of the body.

Q: Do Perricone MD Products Have Retinol?

A: Yes. They have serums that list retinol as their key ingredients. If used correctly and on the right skin types, retinol is considered very effective in skin maintenance as it actively improves collagen levels. In addition, retinol helps diminish hyperpigmentation and acne symptoms.

Q: Is Perricone MD Purely Natural?

A: While the brand values natural ingredients and gives priority to organically sourced constituents, the company admits that they use synthetic ingredients in some of its skincare products. One, some of their skin support serum features clinic-grade acids. In precise the main goal of Perricone MD includes both natural and unnatural ingredients is to boast skin function.

Q: Does Perricone MD Improve Acne?

A: The brand has a special line of acne-fighting products and points out they are committed to bringing in even better solutions. Still, on this, Perricone MD deploys systems that are designed to help deal with acne issues. A system would include several serums, creams and special care that is meant to manage the acne, depending on your skin type.

Q: Is Perricone MD Effective for Sensitive Skin?

A: Yes. Users with skin that gets easily irritated don’t have to worry.  Perricone MD has a category of serums and skin care creams that are designed to care for and improve sensitive skin.

Q: Are Perricone Products Cruelty Free?

A: To answer this, Perricone MD has shared enough information to confirm it as a truly cruelty-free brand. That is, they don’t test any of their ingredients or formulation on animals.

Q: Are Perricone MD Products Any Good?

A: Yes, Perricone MD products are great products. They have been developed by a qualified dermatologist and manufactured using clinically studied ingredients to guarantee quality and effectiveness.

Q: Where Can I Buy Perricone MD?

A: You can purchase Perricone MD products from the brand’s official website. For a buy one, get one free deal, use the promo code BOG022. You get free shipping with orders of $75 or more. If you refer a friend, you can get $50 off.

Perricone MD products are also sold at major department stores such as Nordstrom, Macys and Neiman Marcus, as well as specialty makeup stores such as Blue Mercury, Sephora and Ulta. It is also sold on QVC, Walmart, and Amazon.

The prices of products from this line are as follows:

  • Cold Plasma + Advanced Serum Concentrate – $149.00
  • High Potency Growth Factor Firming and Lifting Serum – $129.00
  • Vitamin C Ester CCC + Feluric Brightening Complex 20% – $159.00
  • Cold Plasma + Sub-D/Neck – $135.00
  • Hypoallergenic CBD Sensitive Skin Therapy _ $69.00
  • Exfoliating and Toning Duo – $69.00
  • No: Rince Pore Minimizing Toner – $45.00
  • DMAE Firming Pads – $80.00
  • No-Rinse Exfoliating Peel – $45.00
Q: How do you take Perricone MD Products?

A: Perricone MD products are different. Some come as serums while others are dietary supplements in the form of capsules. Each product has clear instructions on how you should use it. Read the label carefully to understand user directions.

Q: Are Perricone MD Products Safe?

A: Perricone MD products are designed to help you achieve nothing but the best skincare results. However, if you have any doubts about using any of the products, consult with your physician first.

Q: What is Perricone MD Products Return Policy?

A: All Perricone MD products come with a 14-day money-back guarantee from the date of receiving your order.

Perricone MD Reviews: What Do Customers Think?

The reviews available on the brand’s official website are mostly positive and indicate that products from this line give real results. Most of the customers said that the products gave them even-toned skin with a smooth texture. The brand received an average of 4/5 stars on their website, with very few outliers.

On Influenster, the Perricone MD Vitamin C Ester Serum gets a 4.7 out of 5 star rating from about 3 reviews. Satisfied customers noted “Amazing product! I have really sensitive skin but this vitamin c serum is just so gentle on my skin,I have seen a difference in my dark spots, I have been using this product since 1 month now.”

On Ulta Beauty, the Cold Plasma Plus+ Sub-D/Neck has 4.2 out of 5 star rating, from more than 400 reviews. Some people can’t get past the smell. “After the third day of using it I just couldn’t bear to put it on again. The smell was so offputting.”

The Perricone MD High Potency Classics: Face Finishing & Firming Moisturizer has a higher number of reviews on Amazon; more than 1,000 reviewers gave it 4.5 out of 5 stars. One reviewer noted, “I’ve been using this product for several years. I love that it is lightweight, but still very moisturizing. It also imparts a smooth even finish to my complexion making the use of foundation unnecessary. Nice light scent as well. Worth the money.”

On Trustpilot, Perricone MD received 4.7 stars out of 5. For the most part, reviewers claimed that products were too expensive to repurchase, but most agreed that they saw satisfying results.

In addition, they said it made their skin firm and eliminated wrinkles and lines. I personally read through many, many reviews for this brand and I concluded that they offer very high quality products that users really benefit from. Here are some of the top reviews:

  • Products Which Rescue My Skin

    Cold Plasma is perhaps the most famous product in the Perricone MD line. It is universal, suitable for skin with the first signs of aging, and serves as a base for all care. You can use it alone or combined with other products, since Cold Plasma can conduct cosmetics into the deep layers of the skin. – Emily C

  • Wonderful Cream

    Use it daily for a beautiful, complete routine and lovely skin. Glowing and refreshingly gorgeous skin care. – Robin S.

  • I Never Spend a Lot of Money on Skincare

    I decided to do some research to find an all in one anti-aging product and discovered Cold Plasma by Perricone MD. In a word: WOW. It claimed to treat the 10 visible signs of aging and did it ever! I LOVE this product – it is worth every cent! – Sarah H.

Are Perricone MD Products Worth the Money?

Whether a brand is worth trying or not can depend on several things. One detail that gives this product line advantage is they prioritize natural ingredients. This speaks of safety and clears the fear of side effects. In addition, Perricone MD as a brand is well established and most of its products are considered effective, and without complaints from previous users. In other words, it is safe to conclude that this product line is worth the attention.

Besides, the brand has lots of positive feedback from users both on the official website and retailer sites, a detail that shows the customer reviews are legit. As in, verifiable reviews make it easy for buyers to make an informed decision.

Perricone MD Alternatives

Perricone MD products may not be for everyone- or some of their products just don’t react well with your skin. There are a few other brands to consider.

The Beverly Hills MD product line aims to help people look and feel their very best, by way of the newest, safest, and most promising technology available. On sitejabber, Beverly Hills MD has a consumer rating of 3.88 stars from 112 reviews indicating that most customers are generally satisfied with their purchases. Beverly Hills MD (Beauty Product Brand): 4.4 out of 5 stars from 88 genuine reviews on Australia’s largest opinion site The product Dermal Repair Complex is a revolutionary dietary anti-aging supplement that was designed to help ‘repair’ signs of visible lines and wrinkle.

Founded in 1994, SkinCeuticals is a skin care line dedicated to the research and development of innovative dermatology products.

Contact Information

You have three options:

  1. Call customer service: 888-823-7837 (Monday–Friday, between 9AM and 6PM ET)
  2. Sign in to your Perricone MD account and send a message
  3. Send them a direct message on Facebook, Twitter, or Instagram


Perricone MD produces a wide range of products ranging from anti-aging skincare treatments, eye treatments, Perricone MD Rejuvenating Moisturizers, supplements, Perricone MD Citrus Brightening Cleaners, toners, to masks.

All of these are developed with one goal in mind; to help you achieve healthy skin. However, since skins are different, the user experience may also not be the same. Our team of dermatologists and skin care experts examined the brand closely and concluded that it was a very high level line of skincare.

All in all, provided you follow instructions and you are consistent in the use of these products, you should expect dramatic results in a few weeks. Having used several creams and serums myself, I can tell you this for certain. This is a quality brand of skincare that I would recommend highly.

At Wellness Digest, our sourcing guidelines are strict and we only use primary references for our articles including peer-reviewed studies, academic research institutions, and medical associations. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  1. Anti-inflammatory Diets:
  2. Vitamin C in dermatology:
  3. Using Copper to Improve the Well-Being of the Skin:
  4. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety:
  5. The role of vitamin E in normal and damaged skin:
  6. Skin care in the aging female: myths and truths:
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