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Perricone MD Review – Your Access to Ultra-Rich Beauty Solutions

Perricone MD produces a wide range of products ranging from anti-aging skincare treatments, eye treatments, Moisturizers, supplements, cleaners, toners, to masks.
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Perricone MD
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What is Perricone MD?

Perricone MD is a skincare line of products designed to help repair your damaged skin using nutrient antioxidants.

Products in this line come in three forms; clinical skincare, nutritional supplements, and an anti-inflammatory diet to make you feel and look your best every single day of your life.

The line offers basic skincare solutions ranging from the Perricone MD No Makeup Foundation, Perricone MD No Makeup Lipstick to the Perricone Rejuvenating Moisturizer. Dermatologists highly recommend this brand, and I myself have tried several of the products and was very happy with the results they gave me.


Overview of Perricone MD

Perricone MD


4.8/5Research Supported



Brand Highlights

  • Clinical studies and research supports the ingredients included.
  • The formulas are completely naturally-sourced.
  • They offer a free skincare consultation with a specialist.
  • They support essential workers by offering additional discounts.

Key Ingredients

  • Vitamin E
  • Ferulic Acid
  • Eggshell Membrane
  • Retinol
  • Vitamin C
  • Polyamine Growth Factor
  • Copper Tripeptide
  • Niacinamide
  • Glycerin
  • Omega 3 and 6 Fatty Acids
  • Isopropyl Palmitate


  • It can improve the firmness and elasticity of the skin.
  • Perricone MD can make the skin smooth and radiant.
  • The product can fade the signs of aging such as fine lines and wrinkles.
  • It gives your skin an even tone and texture.
  • Perricone MD can shrink enlarged pores and reduce skin redness.


  • Some people may not like the scent of certain products
  • Some products contain retinol, which may cause a slight reaction in some users.
  • Different users will experience the results differently.
Overall Rating:4.8/ 5

Some of the top-selling products from this brand include:

Cold Plasma + Advanced Serum Concentrate
The Perricone MD Cold Plasma + Advanced Serum Concentrate is a beauty product is designed to promote the 9 most noticeable symptoms of youthful-looking skin.

It works by targeting and improving skin discoloration. It also prevents enlargement of pores, skin redness, wrinkles, fine lines, and loss of skin firmness.Personally, I love this product, and I use it on a daily basis It also makes you experience a radiant and even skin texture and tone.

How to Use
Apply this serum on a cleansed skin. Gently massage it on the face and the area around the neck in an upward motion. Once it is fully absorbed into the skin, apply Perricone MD moisturizer. For better results, ensure you do this twice daily (morning and evening).

Price: $149.00

Ingredients: Vitamin C Ester, Omega 3, 6, & 9, Copper Tripeptide, Aqua, Isopropyl Palmitate, and Glycerin

Vitamin C Ester CCC + Feluric Brightening Complex 20%
The Perricone MD Vitamin C Ester Brightening Serum contains powerful antioxidants and Vitamin C Ester. These components work together to brighten and smoothens your skin as well as give your skin an even tone.

How to Use
Apply it on a cleansed face and the area around the neck then massage it gently using an upward motion. Wait until it is fully absorbed then you can follow with Perricone MD Moisturizer. For best results, apply it twice in the morning and evening.

Price: $159.00

Ingredients: Vitamin C Ester, Ferulic Acid, Vitamin E, Aqua, 3-O-Ethyl Ascorbic Acid,

High Potency Growth Factor Firming and Lifting Serum
It is a powerful day and night cream designed to give your skin a dramatic lifting effect to give it a smooth and radiant appearance. It works by supporting the skin moisture barrier and visibly improves its suppleness, cushion, bounce, strength, and resiliency.

How to Use

Apply it on a cleansed face and area around the neck. Massage it gently using an upward motion. Once it is fully absorbed, follow it with Perricone MD Moisturizer. For best results, apply it in the morning and evening.

Price: $129.00

Ingredients: Polyamine Growth Factor, Eggshell Membrane, Encapsulated Retinol, Niacinamide,


About the Brand: Who Owns Perricone MD?

Perricone MD a skincare company owned by Dr. Nicholas Perricone, who is an expert in healthy aging, a board-certified dermatologist, and an award-winning inventor. He has over 116 U.S and International patents for the treatment of systematic diseases and damage to the skin.

The doctor founded the company in 1997, and has since become the leading authority there on the science of fine-looking skin. He continues to make breakthroughs in the field of skincare.

Perricone MD


What are the Active Ingredients in Perricone MD Products?

Vitamin C Ester

Vitamin C Ester is a potent antioxidant that supercharges the smoothing and brightening of the skin. It is the key ingredient in the Perricone MD Vitamin C Ester Brightening Serum and is specifically meant to give the skin a collagen-rich appearance, by minimizing the discoloration on your skin over time.

It does this by blocking the production of melanin on the skin, for lightening benefits. It can fade dark spots and areas of discoloration. Vitamin C Ester also hydrates the skin and eliminates dryness. It has anti-aging benefits and can help smooth wrinkles and fine lines.

Unlike other Vitamin C, this one is a fat-soluble and easy-to-absorb nutrient that maximizes antioxidant benefits. According to the Indian Dermatology Online Journal, Vitamin C contains potent antioxidant properties. It is used in dermatology treatments and prevents photoaging-related changes.

Copper Tripeptide

Copper Tripeptide is in the form of amino acid, and it works to improve the feel and look of skin’s firmness and thickness. It is one of the key ingredients in the Perricone MD Cold Plasma Plus+ Eye. The topical application of this tripeptide can improve the appearance of damaged skin, including sagging and wrinkles.

According to Current Chemical Biology, copper has been found to stimulate dermal fibroblasts proliferation as well as upregulating collagen and elastin fiber components. This helps firm the skin, improve elasticity, and smooth wrinkles and lines.

It also serves as biosynthesis, an enzyme responsible for skin pigmentation. It promotes even skin tone, eliminating age spots and acne scars. Copper tripeptides are high in anti-inflammatory agents which can reduce redness and swelling on the skin.

Encapsulated Retinol

Encapsulated Retinol is a stabilized retinol. It is used in cosmetic products to replenish the look of collagen-depleted thin skin by accelerating skin surface renewal. It is the key ingredient of the Perricone MD Firming and Lifting Serum.

This is Vitamin A, which is a powerful antioxidant which can repair skin barrier damage and protect from UV rays and pollutants. It’s also a potent exfoliant which can remove dead skin cells and dirt from the pores and help to heal acne. According to Clinical Intervention in Aging, retinoid is a potent anti-aging agent widely studied and available for the treatment of age-related symptoms.

Vitamin E

Vitamin E is a potent ingredient that provides the skin with a super nourishment effect. Its hydrating and reparative antioxidant properties aid in minimizing the appearance of discoloration on the skin, and can improve both tone and texture.

It can repair damage to the skin and protect it from UV rays. Vitamin E is also high in anti-inflammatory benefits, which can decrease redness and swelling and help to treat skin conditions.

According to the Journal of Molecular Science, Vitamin E is a naturally occurring non-enzymatic and lipid-soluble antioxidant found to protect the skin from oxidative stress adverse effects, including photoaging.


How Does Perricone MD Work?

Each product from this line is designed to benefit your skin differently. So, the product choice will depend on the kind of skin concern you have.

There are cleaners whose work is to get rid of debris that clog the pores and make your skin’s complexion dull. There are also treatments that address common skin concerns to ensure that your skin appears healthier and more attractive.

Lastly, there are hydration products that help restore the potent moisture skin barrier, leaving you feeling and looking your best.


Frequently Asked Questions (FAQs)

Q: Is Perricone MD Cruelty Free?

A: To answer this, Perricone MD has shared enough information to confirm it as a truly cruelty-free brand. That is, they don’t test any of their ingredients or formulation on animals.

Q: Are Perricone MD Products Any Good?

A: Yes, Perricone MD products are great products. They have been developed by a qualified dermatologist and manufactured using clinically studied ingredients to guarantee quality and effectiveness.

Q: Where Can I Buy Perricone MD?

A: You can purchase Perricone MD products from the brand’s official website. For a buy one, get one free deal, use the promo code BOG022. You get free shipping with orders of $75 or more. If you refer a friend, you can get $50 off.
The prices of products from this line are as follows:

· Cold Plasma + Advanced Serum Concentrate – $149.00
· High Potency Growth Factor Firming and Lifting Serum – $129.00
· Vitamin C Ester CCC + Feluric Brightening Complex 20% – $159.00
· Cold Plasma + Sub-D/Neck – $135.00
· Hypoallergenic CBD Sensitive Skin Therapy _ $69.00
· Exfoliating and Toning Duo – $69.00
· No: Rince Pore Minimizing Toner – $45.00
· DMAE Firming Pads – $80.00
· No-Rinse Exfoliating Peel – $45.00

Q: How do you Take Perricone MD Products?

A: Perricone MD products are different. Some come as serums while others are dietary supplements in the form of capsules. Each product has clear instructions on how you should use it. Read the label carefully to understand user directions.

Q: Are Perricone MD Products Safe?

A: Perricone MD products are designed to help you achieve nothing but the best skincare results. However, if you have any doubts about using any of the products, consult with your physician first.

Q: What is Perricone MD Products Return Policy?

A: All Perricone MD products come with a 14-day money-back guarantee from the date of receiving your order.


What Do Perricone MD Reviews Say?

 The reviews available on the brand’s official website are mostly positive and indicate that products from this line give real results. Most of the customers said that the products gave them even-toned skin with a smooth texture.

In addition, they said it made their skin firm and eliminated wrinkles and lines. I personally read through many, many reviews for this brand and I concluded that they offer very high quality products that users really benefit from. Here are some of the top reviews:

  • Products Which Rescue My Skin

    Cold Plasma is perhaps the most famous product in the Perricone MD line. It is universal, suitable for skin with the first signs of aging, and serves as a base for all care. You can use it alone or combined with other products, since Cold Plasma can conduct cosmetics into the deep layers of the skin. – Emily C

  • Wonderful Cream

    Use it daily for a beautiful, complete routine and lovely skin. Glowing and refreshingly gorgeous skin care. – Robin S.

  • I Never Spend a Lot of Money on Skincare

    I decided to do some research to find an all in one anti-aging product and discovered Cold Plasma by Perricone MD. In a word: WOW. It claimed to treat the 10 visible signs of aging and did it ever! I LOVE this product – it is worth every cent! – Sarah H.



Perricone MD produces a wide range of products ranging from anti-aging skincare treatments, eye treatments, Perricone MD Rejuvenating Moisturizers, supplements, Perricone MD Citrus Brightening Cleaners, toners, to masks.

All of these are developed with one goal in mind; to help you achieve healthy skin. However, since skins are different, the user experience may also not be the same. Our team of dermatologists and skin care experts examined the brand closely and concluded that it was a very high level line of skincare.

All in all, provided you follow instructions, and you are consistent in the use of these products, you should expect dramatic results in a few weeks. Having used several creams and serums myself, I can tell you this for certain. This is a quality brand of skincare that I would recommend highly.

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[1] Anti-inflammatory Diets:

[2] Vitamin C in dermatology:

[3] Using Copper to Improve the Well-Being of the Skin:

[4] Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety:

[5] The role of vitamin E in normal and damaged skin:

[6] Skin care in the aging female: myths and truths: