Nucific Prebio Cleanse Reviews: Does It Help Improve Your Gut Health?

Prebio Cleanse is a digestive-cleansing supplement made by the Nucific brand. A natural blend of five prebiotics that boosts gut wellness.
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What is Prebio Cleanse?

Prebio Cleanse is a digestive-cleansing supplement made by the Nucific brand. This natural product is a blend of five powerful prebiotics that boosts gut wellness by mitigating better digestion, increasing energy, and quenching hunger.

When it comes to the digestive system, everybody can hope to improve their digestion and overall health by creating the right balance in the variety of bacteria in their gut. In other words, the beneficial bacteria’s population in the digestive tract and its right amount play a significant role in its functioning as well as the overall health of the body. One of the factors affecting that balance is having a proper diet, especially prebiotics that can modify digestion.

Prebiotics, often classified as dietary fibers, act as carbon sources for fermentation pathways in the colon, and support digestive health in many ways. Consequently, supplements rich in prebiotics can be beneficial for the gastrointestinal tracts.

The all-natural ingredients in Prebio Cleanse help optimize gut health, render smoother digestion, and suppress unnecessary cravings, which in general lead to a more energized person.
Let’s continue reading to learn more about Prebio Cleanse, its brand, and whether it is an effective option for rectifying gut health.

Prebio Cleanse

Prebio Cleanse – Image/Wellness Digest

About the Brand

Nucific is a California-based company manufacturing Prebio Cleanse, operational since 2016. The “A+” rated company with over 8 million in revenue has 45 employees and has become a top-rated label so far.

The producers explicitly insist on not using artificial sweeteners or colorants on their official website, unlike other supplement companies. Their most demanded products include: Bio X4, Moro-Slim, Prebio-Boost, and Deep Cell Activator are some of their other products.

Overall Rating

Prebio Cleanse





Brand Highlights

  • All-Natural ingredients
  • A 5-in-1 prebiotic blend
  • Manufactured in The US
  • GMP-Certified Facility
  • It Has a 90-Day Guarantee

Key Ingredients

  • Inulin
  • Konjac Root
  • Oat Fiber Extract (15% B-Glucan)
  • L-arabinose
  • Fructooligosaccharides


  • Modify gut health
  • Causes smoother digestion
  • Suppresses hunger
  • Creates more energy
  • Customer feedback is generally favourable.
  • It is made of all-natural prebiotics with no known adverse effects.
  • The brand offers a 90-day refund policy.
  • The website is user-friendly with excellent customer service.


  • This product is only available on the official website.
  • Although safe, taking an exact dosage is recommended to avoid adverse effects and discomfort.
  • Check drug interaction with other supplements you use.
Overall Rating:4.8/ 5

Key Facts

😊 Benefits It modifies gut health, causes smoother digestion, suppresses hunger & creates more energy
💊 Ingredients Silicon Dioxide
✅ Discounts With 3 and 6 jars comes respectfully 10% and 15% discount + free shipping
🏢 Company Nucific
⚥ Age Group Adults
Form Gel
👫 Gender Unisex

How Does Prebio Cleanse Work?

Prebio Cleanse comprises a formula with 5 “prebiotics” components that can regulate the colon’s processes, like a gut cleanser which can also curb appetite and help lose weight.

Prebiotics are, in fact, nutrients degraded by gut microbiota. Their relationship with overall human health has been an area of increasing interest in recent years. Prebiotics are most famous for feeding the intestinal microbiota, as their degradation products are short-chain fatty acids released into blood circulation. As a result, they can affect the gastrointestinal tracts, and on top of that, other distant organs can function better as well.

What are the Ingredients in Prebio Cleanse

The key ingredients inside Prebio Cleanse are five potent prebiotics as follows:

  • Inulin
  • Konjac Root
  • Oat Fiber Extract (15% B-Glucan)
  • L-arabinose
  • Fructooligosaccharides


Inulin is a type of fiber carbohydrate which isn’t digested or absorbed, instead absorbs water and expands in the stomach, creating the feeling of fullness. Other benefits of this prebiotic include supporting blood glucose levels, weight loss, and digestion improvement.

There have been studies to confirm inulin supplementation’s impact on the cardiometabolic health of the body. According to a randomized study, constipated patients that took 12 g of inulin daily for four weeks had higher stool frequency, softer stools, and increased levels of gut activity.

Konjac Root

Konjac root, also known as elephant yam, is a high-fiber plant root. It grows in parts of Asia and provides its consumers with plenty of health benefits such as reducing blood glucose, cholesterol, triglycerides, and blood pressure and can enable weight loss.

With a diet high in fiber like that, you can expect refreshing results of bowel movement regulation, preventing haemorrhoids, and avoiding diverticular disease.

Oat Fiber Extract (15% β-glucan)

Oat β-glucan has been shown to affect lipid and cholesterol metabolism positively. Although, the mechanisms behind the beneficial impact have not been wholly understood.

Glucan, the soluble fiber in oats, helps with hunger control, most likely due to the glucan’s sticky texture, which impedes digestion and creates a feeling of false fullness. Doses ranging from 2.2 to 5.5g per day appear to lower hunger in healthy subjects over a few hours.


L-Arabinose is a simple sugar derived from the side-streams of plant food processing. This bio-active compound can play an essential role in managing blood glucose and insulin levels related to sucrose intake. It has been shown to have protective effects in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats.

Another study indicated that l-Arabinose lowers glycemic and insulinemic responses when added to simple water-based sugary liquids. However, its impact on more complex foods, like fat and starch, was inconsistent.


Fructooligosaccharides (FOS) Other non-digestible carbohydrates are found naturally in plants such as onion, chicory, garlic, asparagus, banana, artichoke, etc. Their potential health benefits include low carcinogenicity, prebiotic effect, improved mineral absorption, decreased serum cholesterol levels, triacylglycerols, and phospholipids.

Due to their prebiotic effect, they can stop nonpathogenic intestinal microflora, increase the frequency of depositions and reduce constipation. These are hypothesized to lower appetite by rendering a sensation of fullness as inulin, and other kinds of fiber do.

Frequently Asked Questions

Q: How should I Take Prebio Cleanse?

A: It has been recommended to combine one scoop of Prebio Cleanse with 8 ounces of water and drink once daily. To see the best results in reducing unwanted cravings, you should drink before it night or first thing in the morning.

Q: How Long Does It Take To Produce Results?

A: It is true that every individual digestive system works uniquely; however, based on Prebio Cleanse consumers’ feedback, it takes at least 60 days to witness the maximum results. With a 90-day money-back guarantee,  you can always feel free to ask for a refund within that time if you’re not satisfied.

Q: What Happens If I Miss a Day?

A: You better not take it regularly to ensure that your body is getting enough prebiotics. However, if you skip a day, just resume your regular schedule the next day.

Q: Where Can I Buy Prebio Cleanse?

A: Right now, Prebio Cleanse is only available through the Nucific official website.

Q: What Is The Price Of Prebio Cleanse?

A: 1 Jar: $ 64.95 (plus shipping)

Q: Is There a Refund Policy?

A: Nucific brand offers a 90-day money-back guarantee on their products. If you are unsatisfied with your purchase, you may ask for a full refund.

 Q: Is Prebio Cleanse Safe?

A: Inulin and fructooligosaccharides have been studied at doses 3-4x larger than what is offered in the combined total of Prebio Cleanse, without serious side effects. Plus, for prebiotics in general, only mild and self-limiting side effects have been reported.

What Do Reviewers Think of Prebio Cleanse?

  • As requested, I started drinking it every night before I went to bed, just to get a regular bowl movement and feel better while sleeping. But it s actually making me feel less hungry, and I lost weight over time. Kudo to you guys for this miracle drink!Alison
  • My digestive system was a mess, and I suffered awful symptoms of diarrhea, gas, and bloating over time. But now, with this drink, I feel so much better. My gut settled, and I’m grateful for this blend.Jonathan
  • Honestly, I thought it would be fake because of a few ingredients, but it is terrific. I can tell the difference using the prebio cleanse with regular bathroom visits and fewer tummy aches and bloating. Pamela

How to Order Prebio Cleanse

Customers can only buy Prebio Cleanse directly from the Official Website. You can go for different packaging, although if you purchase multiple jars (3 or 6), there are considerable discounts, 10% and 15%, and you also benefit from free shipping.

The following pricing options are available for purchase:

  • 1 Jar: $64.95 + Shipping
  • 3 Jars: $173.85 (save $21) Free Shipping
  • 6 Jars: $329.70(save $60) Free Shipping

Nucific company backs its products with a 90-day guarantee. Therefore, if customers are not satisfied with the outcome for some reason, they can always call for a full refund.
Customer Service Contact Info:

Phone: 888-679-5520 Mon-Fri 5AM-7PM PST Sat-Sun 6AM-4:30PM PST

Email: [email protected]

Address: 30700 Russell Ranch Rd Westlake Village, CA 91362

How Does It Compare to Other Similar Products?

Multi-GI 5 Gundry MD Bio Complete 3 1MD EnzymeMD
Product Highlights

  • It can give you increased energy.
  • The product supports healthy digestion.
  • reduces the symptoms of bloating and gas.
  • It helps with weight management.
  • can strengthen the immune system.


  • There is only one flavor option, which is strawberry lemonade.
  • You may experience mild side effects like stomach upset for a couple of days.
  • The results will vary for different customers.
Product Highlights

  • The product can help you maintain a slimmer waistline.
  • It can improve daily energy levels.
  • supports smoother digestion.
  • It can reduce cravings for junk food.
  • The supplement can reduce bloating.


  • The results will vary for different individuals.
  • You have to take 4 capsules daily.
  • They could add additional ingredients.
Product Highlights

  • It can decrease gas, indigestion, and bloating after eating.
  • The product can get rid of toxic gases.
  • contains enzymes which can break down nutrients.
  • A board-certified gastroenterologist designed it.
  • can improve digestive health.


  • The results will vary for different individuals.
  • You have to take 4 capsules daily.
  • They could add additional ingredients.


Prebio Cleanse is a potent gut cleanser with five natural prebiotics helping your digestive system thrive. Online reviews are mostly positive, and this product doesn’t carry any complaints. There is barely any negative feedback relating to the product itself; some might’ve called it pricy or bought it from unreliable outlets. However, this unique blend has hardly any comparison that can help weight loss and act as a digestion supplementation.

At Wellness Digest, our sourcing guidelines are strict and we only use primary references for our articles including peer-reviewed studies, academic research institutions, and medical associations. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  1. The Effect of Prebiotic Supplementation with Inulin On Cardiometabolic Health: Rationale, Design, and Methods Of A Controlled Feeding Efficacy Trial in Adults at Risk of Type 2 Diabetes
  2. The impact of oat structure and ß-glucan on in vitro lipid digestion
  3. Dietary fiber and satiety: the effects of oats on satiety
  4. Efficacy of L-Arabinose in Lowering Glycemic and Insulinemic Responses: The Modifying Effect of Starch and Fat
  5. Dietary fructooligosaccharides and potential benefits on health
  6. Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications
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